96% showed visibly firmer skin in 12 weeks with the OS-01 Peptide™, the first peptide proven to reverse skin's biological age.
What you see. Skin that feels less firm, with less bounce and more fine lines.
What causes it. As we age, senescent cells build up: skin cells that stop working but don't go away. They break down the collagen and elastin that keep skin firm and bouncy.
That's why OneSkin created OS-01 FACE Moisturizer with the OS-01 Peptide™, which targets these aging cells so skin looks firmer over time.
Built on over a decade of longevity science, the OS-01 Peptide™ targets senescent cells, the aging cells that break down collagen, elastin, hyaluronic acid and barrier strength.
A temporary tightening that washes off.
Works on: SurfacePlump the surface for a few hours.
Works on: SurfaceWork on specific areas, with appointments and recovery time.
Works on: One spotTargets aging cells to help skin look firmer over time, in your daily moisturizer.
Works on: aging skin cells
✓ Fewer lines
✓ Smoother forehead
✓ Fewer fine linesof participants showed more even tone, radiance and visible firmness
of participants had improved elasticity
of participants showed visibly smoother texture
Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65 (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024). Individual results vary.
Lightweight hydration that absorbs instantly.
+19% skin barrier resilience.¹
96% showed visibly firmer skin.¹
I’ve been including OS-01 face topical supplement in my skin care routine for about a year. I can honestly say I have seen an improvement in the texture and firmness of my skin. Even my esthetician has noticed!
Ruth K.OS-1 Face is a terrific product! I’ve been using it for several years and have been really happy with the results: firmer skin and more even tone. I also appreciate the refillable pouch - less waste is always a good thing 😄
Kelly R.This is my second refill, and I am really seeing healthier looking skin. My skin is smoother, firmer, and well moisturized.
Lisa G.Been using for a couple years and it works well, keeps my skin healthy and makeup goes on well after
Cara B.My skin is less dry, wrinkles less pronounced. makeup goes on easier and I've had compliments on how nice my face looks
Anne M.I’m 58 and this is the only product I use on my face! Works perfectly under makeup and I’ve noticed that my skin seems to have less fine lines and wrinkles have softened.
Nancy S.One Skin is as good or better than the super pricey products that I have tried at MedSpas. In addition, I feel great about using refills so as to discard less plastic waste.
Judy C.I have sensitive skin with rosacea that reacts to everything. Since starting OneSkin my skin has never felt or looked better! It's a wonderful product at a reasonable price point....I'll use it forever!
Elliott C.The science is real on os-1. I use it daily and have for 5 years. Worth it!
Michele M.I have very sensitive skin + rosacea & pretty much every other facial brand I've tried inflames it. Very glad I tried this product. Unscented, no flareups, and it keeps my face nicely moisturized and healthy-looking, no longer blotchy & flaky.
Bridget D.I've really noticed a change since starting to use it, and what's best is, it doesn't irritate my skin at all, and I have really sensitive skin.
Eric B.Repeat purchase. My sensitive skin does very well with this moisturizer. No breakouts, eczema or pilling with makeup.
Kayla C.Liked it enough to subscribe, which I almost never do with any product. One Skin is awesome.
Catherine B.The auto-order feature is so easy and if I need to delay the order, that is easy as well. It feels good to reuse the plastic shell. I keep using the product because I like the way it absorbs into my skin and keeps my skin feeling supple.
Linda F.I have been using this product for years now, the fact that I can get the refill instead of a whole new bottle is great. I find it easy to replace.
Tamara S.
Lightweight hydration clinically shown to firm and smooth skin.
Free shipping on orders $79+
Try it risk-free for 30 days
You're earning 100 points with the OneSkin Loyalty Program
Certified cruelty-free by The Leaping Bunny
Approved by the National Eczema Association
Certified plastic neutral in partnership with RePurpose
Clinically tested to support the skin microbiome¹Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65 (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
OS-01 Peptide™ · Oleic pau mulato extract (supports skin's natural repair processes) · Niacinamide (visibly improves skin texture and tone) · Hyaluronic acid (triple-weight complex hydrates each layer of the skin)
Dispense 1-2 pumps onto fingers. Gently massage into skin on the face and neck. Use 2x daily.
On the recommended every-2-months plan it works out to about $1.65 a day, and your first order is risk-free for 30 days.
Yes. It's fragrance free, suitable for sensitive skin and approved by the National Eczema Association. As with any new product, patch test first.
After cleansing, dispense 1–2 pumps and massage into face and neck, morning and night. Finish with SPF in the morning.
Yes. It has not been shown to react with common actives like vitamin C or hyaluronic acid. As with any new product, patch test first.
Skin feels hydrated right away. Firmness, lines and texture were measured at 12 weeks in the clinical study.
Yes. Change, skip or cancel anytime from your account.
Every first order is risk-free for 30 days.